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NÜKLEİK ASİT
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NÜKLEİK ASİT
(Medicine and Hematology Glossary) :
Kimyasal olarak birbirine bağlanmış nükleotidlerden oluşan yapı. Nükleotidlerdeki şeker molekülü riboz ise oluşan nükleik asit RNA, şeker molekülü 2-deoxyriboz ise DNA'dır. Nükleotidlerin birbirine tutunmaları özellik gösterir. Nükleotiddeki pentozun 3' karbon (C) kısmındaki hydroxyl (OH) içeren uç ile fosfat (P) bulunan 5' ucu bağlanır. Bu bağlanmalarla oluşan nükleik asitin de baş kısmında 5' P ucu, sonunda da 3' OH ucu vardır. DNA'da olduğu gibi iki nükleik asit zinciri bulunan yapıların uçlarında 3' ve 5' uçlar birbiriyle karşılıklı gelirler.
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